PREVALENCE / INCIDENCE
OF SINGLE UMBILICAL ARTERY (SUA)
CONDITIONS ASSOCIATED WITH AN INCREASED INCIDENCE OF
SUA
More frequent in Eastern
European females.
Lower frequency in Japanese
and African females.
Young primiparous women.
Maternal diabetes.
Epilepsy.
Hypertension / toxemia.
Antepartum hemorrhage.
Polyhydramnios.
Oligohydramnios.
FACTORS INFLUENCING THE INCIDENCE OF SUA
Population being considered.
Method of examination
(prenatal ultrasound,
Assessment at delivery or histologically).
Portion of cord examined.
Parity.
Maternal race.
INCIDENCE
1.5-7% among abortuses (2,3).
0.2-1.6% among euploid
fetuses undergoing prenatal ultrasound examination. (4,5).
9-11% among aneuploid fetuses
(6,7).
0.5-2.5% among uncomplicated
neonates (8,9).
REFERENCES
Persutte WH, Hobbins J.
Single umbilical artery: a clinical enigma in modern prenatal diagnosis.
Ultrasound Obstet Gynecol 1995;6:216-229.
Bryne J, Blanc WA. Malformations
and chromosomal anomalies in spontaneously aborted fetuses with single
umbilical artery. Am J Obstet Gynecol 1985;151:340-342.
Csecsi K, Kovacs T,
Hinchliffe SA et.al. Incidence and associations of single umbilical artery
in prenatally diagnosed malformed midtrimester fetuses: a review of 62
cases. Am J Med Genet 1993;43:524-530.
Jones TB, Sorokin Y, Bhatia
R et.al. Single umbilical artery: accurate diagnosis? Am J Obstet Gynecol
1993;169:538-540.
Herrmann UJ, Sidiropoulos D.
Single umbilical artery: prenatal findings. Prenat Diagn 1988;8:275-280.
Saller DN, Keene CL, Sun C,
Schwartz A. Am J Obstet Gynecol 1990;163:922.
Khong TY, George K.
Chromosomal abnormalities associated with a single umbilical artery.
Prenat Diagn 1992;12:965-968.
Leung AKC, Robson WLM.
Single umbilical artery. Am J Dis CHILD 1989;143:108-111.
Khong TY, George K.
Chromosomal abnormalities associated with a single umbilical artery.
Prenat Diagn 1992;12:965-968.